Transformation of lymphocytes from fresh blood to produce lymphoblastoid cell lines (LCLs), as well as transformation of cryopreserved lymphocytes isolated from blood.

Large-scale growth of lymphocyte or other cell lines for DNA/RNA extraction and/or cryopreservation.

Extraction of high molecular weight, PCR-amplifiable DNA from blood, cultured cells, or tissue samples.

Separation and storage of plasma or other biomaterials from whole blood.

Whole genome DNA amplification for samples containing very limited amounts of DNA, or where no cell line exists.

Shipment of biomaterials (cell lines and nucleic acids) under government approved conditions that maintain sample viability and integrity.

Molecular genetics diagnostic services including verification of pedigree relationships and DNA diagnostics for common genetic diseases using state of the art instrumentation. Assays supervised by American Board of Medical Genetics certified Clinical Molecular Geneticists.

Consultation or assistance with the design of new projects.

Production of common genetic maps from independent studies of the same disorder, and application of novel analytical approaches to phenotypic and genotypic data.

The RUCDR bioinformatics resource resolves linkage or genotyping discrepancies within families, projects, or multiple data sets, thus enabling identification of candidate gene regions for common diseases.

Whole genome and regional SNP genotyping using several different technology platforms.

High-throughput robotics for arraying genomic DNA in tubes or microwell plates and for arraying oligonucleotides on glass slides or membranes.

Gene expression surveys, including data analysis, using custom or prefabricated oligonucleotide microarrays or real-time PCR.

High-throughput, microchip assays of nucleic acids and proteins.