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Analytical Facilities

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The analytical facilities at RUCDR Infinite Biologics are comprised of a variety of instrumentation that utilize cutting-edge technologies. The large breadth of coverage provided by this facility enables comprehensive services in epigenetics, genomics, and gene expression.

Epigenetics

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RUCDR utilizes cutting edge microarray and Next-Generation Sequencing platforms to achieve genome-wide detection of epigenetic events.

  • Affymetrix GeneChip® and GeneTitan® Systems for all Affymetrix Genotyping products
  • Illumina MiSeq Personal Sequencer produces 8.5 Gb of high-quality sequence data in less than 40 hours
  • Illumina HiSeq 2000 provides industry leading sequencing throughput (600Gb in a single run)

Genomics

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RUCDR has a fully automated robotics facility for production of custom DNA formats, SNP and microsatellite genotyping, Next Generation sequencing, and genetic testing.

  • ABI 7900HT - This quantitative PCR System combines 96- and 384-well formats with fully automated robotic loading and fast real-time PCR capability.
  • ViiA 7 Instruments - This high performance instrument, delivers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation for high-productivity real-time PCR processing.
  • Fluidigm BioMark™ System using 96.96 and 48.48 Dynamic Arrays – capable of 9,200 genotypes in picoliter volumes in 90 min.
  • Wafergen™ SmartChip Catalogue and MyDesign™ Arrays – capable of 5000+ genotypes in any sample or assay format desired.
  • Beckman Coulter GenomeLab™ SNPstream® Genotyping System - capable of performing from 4,600 to over 3,000,000 SNP genotypes per day.
  • Affymetrix GeneChip® and GeneTitan® Systems for all Affymetrix Genotyping products
  • Illumina iScan Systems for all Illumina Genotyping products.
  • NuGEN Mondrian and Caliper SciClone systems for fully automated construction of sequencing libraries
  • Ion Torrent Semiconductorsequencing on the Ion Personal Genome Machine™ (PGM). 314, 316 and 318 chips produce up to 10Mb, 100Mb and 1Gb of raw sequence data in less than 5 hours
  • Illumina MiSeq Personal Sequencer produces 8.5 Gb of high-quality sequence data in less than 40 hours
  • Illumina HiSeq 2000 provides industry leading sequencing throughput (600Gb in a single run)

Gene Expression

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RUCDR Infinite Biologics analytical facilities include instrumentation capable of low to medium and high throughput microarray-based solutions for gene profiling studies.

  • Affymetrix GeneChip® and GeneTitan® Systems for all Affymetrix gene profiling products
  • Illumina iScan System for all Illumina microarray products
  • Agilent CGH arrays, Invitrogen NCode arrays
  • Applied Biosystems ViiA™ 7 Real-Time PCR System- This high performance instrument delivers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation. This system combines 96 and 384-well formats with fully automated robotic plate loading for high-productivity real-time PCR processing.
  • Fluidigm BioMark™ System using 96.96 and 48.48 Dynamic Arrays – capable of 9,200 real-time qPCR reactions in picoliter volumes in a single run. Digital PCR arrays enable ultrahigh-resolution and absolute molecule quantification for gene copy number experiments.
  • Wafergen™ SmartChip Catalogue and MyDesign™ Arrays – capable of 5000+ real-time qPCR reactions with flexible sample and assay formats.
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145 Bevier Road Piscataway NJ 08854-8009
p 732 445 1498 f 732 445 1149 www.rucdr.org